Article
Low REST Expression Indicates a Biomarker of Poor Prognosis in Patients with Renal Cell Carcinoma.
BioMed research international - 1 Jan 2021
Lv Chaoxiang, Li Yuanguo, Zhang Qiqi, Chen Yanyan, Wei Dandan, Wang Tiecheng, Zhou Bo
Abstract excerpt
It was initially found that neural-restrictive silencer factor/repressor 1-silencing transcription factor (REST) is a transcriptional repressor of neuronal genes in nonneuronal cells. However, it is reported to be abundantly expressed in various types of aggressive cancer cells. In this study, we evaluated the expression patterns of REST in renal cell carcinoma and found that its expression is lower in tumor...
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