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Article

Regulation of the NRSF/REST gene by methylation and CREB affects the cellular phenotype of small-cell lung cancer.

Oncogene - 28 Oct 2010

Kreisler A, Strissel P L, Strick R, Neumann S B, Schumacher U, Becker C-M

Abstract excerpt

The neuron-restrictive silencer factor/RE1-silencing transcription factor (NRSF/REST) is a negative regulator of gene expression restricting the expression of neuronal genes to the nervous system. NRSF/REST is highly expressed in non-neuronal tissues like the lung. In previous work, we identified...

Read the complete abstract on PubMed

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20697351
DOI: 10.1038/onc.2010.321

Genes

REST
AKT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20697351-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Regulation of the NRSF/REST gene by methylation and CREB affects the cellular phenotype of small-cell lung cancer.PMID 20697351Read ↗

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