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Article

Choice of assemblers has a critical impact on de novo assembly of SARS-CoV-2 genome and characterizing variants.

Briefings in bioinformatics - 2 Sept 2021

Islam Rashedul, Raju Rajan Saha, Tasnim Nazia, Shihab Istiak Hossain, Bhuiyan Maruf Ahmed, Araf Yusha, Islam Tofazzal

Abstract excerpt

BACKGROUND: Coronavirus Disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a global pandemic following its initial emergence in China. SARS-CoV-2 has a positive-sense single-stranded RNA virus genome of around 30Kb. Using next-generation sequencing technologies, a large number of SARS-CoV-2 genomes are being sequenced at an unprecedented rate and being...

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Identifiers

PMID: 33822878
DOI: 10.1093/bib/bbab102
PMCID: PMC8083570

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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