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Article

Why Inhibition of IL-23 Lacked Efficacy in Ankylosing Spondylitis.

Frontiers in immunology - 1 Jan 2021

McGonagle Dennis, Watad Abdulla, Sharif Kassem, Bridgewood Charlie

Abstract excerpt

The term spondyloarthritis pertains to both axial and peripheral arthritis including ankylosing spondylitis (AS) and psoriatic arthritis (PsA), which is strongly linked to psoriasis and also the arthritis associated with inflammatory bowel disease. The argument supporting the role for IL-23 across the spectrum of SpA comes from 4 sources. First, genome wide associated studies (GWAS) have shown that all the...

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Identifiers

PMID: 33815371
DOI: 10.3389/fimmu.2021.614255
PMCID: PMC8017223

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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