Article
[Spondyloarthritis].
Zeitschrift fur Rheumatologie - 1 Nov 2018
Syrbe U, Baraliakos X
Abstract excerpt
Spondyloarthritis (SpA) describes the group of inflammatory diseases characterized by inflammation within axial joints and/or peripheral arthritis, enthesitis, and dactylitis. Disease development is strongly determined by genes and particularly associated with the presence of HLA-B27. Transgenic expression in animal models leads to induction of a SpA-like disease, suggesting a direct effect of HLA-B27 on disease...
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