Article
Why did IL-23p19 inhibition fail in AS: a tale of tissues, trials or translation?
8 Oct 2018
Abstract excerpt
Figure There is now increasing evidence suggesting that different cytokines may enjoy distinct hierarchical roles in tissues across the spondyloarthritis spectrum. This figure highlights those pathways with demonstrable effects in each discrete tissues against those in which clinical responses were not observed. In the absence of formal head-to-head studies, these comparators should be taken as potential rather...
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