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Article

Targeting the YAP/TAZ Pathway in Uveal and Conjunctival Melanoma With Verteporfin

2 Apr 2021

Abstract excerpt

Purpose: The purpose of this study was to determine whether YAP/TAZ activation in uveal melanoma (UM) and the susceptibility of melanoma cell lines to YAP/TAZ inhibition by verteporfin (VP) is related to the tumor's genetic background. Methods: Characteristics of 144 patients with enucleated UM were analyzed together with mRNA expression levels of YAP/TAZ-related genes (80 patients from the The Cancer Genome...

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PMID: 33798262
DOI: 10.1167/iovs.62.4.3

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