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Article

High expression of lncRNA PVT1 independently predicts poor overall survival in patients with primary uveal melanoma

15 Dec 2017

Abstract excerpt

The plasmacytoma variant translocation 1 gene (PVT1) plays an oncogenic role in the initiation and progression of multiple cancers. In this study, by using deep-sequencing data and follow-up data in the Cancer Genome Atlas-Uveal melanomas (TCGA-UVM), we assessed the association between the expression of PVT1 and clinicopathological characteristics of patients with uveal melanoma, the mechanism of its...

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PMID: 29244840
DOI: 10.1371/journal.pone.0189675

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