Fast effect size shrinkage software for beta-binomial models of allelic imbalance.

doi:10.12688/f1000research.20916.2

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Article

Fast effect size shrinkage software for beta-binomial models of allelic imbalance.

F1000Research - 1 Jan 2019

Zitovsky Joshua P, Love Michael I

Abstract excerpt

Allelic imbalance occurs when the two alleles of a gene are differentially expressed within a diploid organism and can indicate important differences in cis-regulation and epigenetic state across the two chromosomes. Because of this, the ability to accurately quantify the proportion at which each allele of a gene is expressed is of great interest to researchers. This becomes challenging in the presence of small...

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PMID: 33796271
DOI: 10.12688/f1000research.20916.2
PMCID: PMC7974632.2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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