Article
APOL1 at 10 years: progress and next steps.
Kidney international - 1 Jun 2021
Freedman Barry I, Kopp Jeffrey B, Sampson Matthew G, Susztak Katalin
Abstract excerpt
APOL1 kidney risk variants (RVs) were identified in 2010 as major drivers of glomerular, tubulointerstitial, and renal microvascular disease in individuals with sub-Saharan African ancestry. In December 2020, the "APOL1 at Ten" conference summarized the first decade of progress and discussed controversies and uncertainties that remain to be addressed. Topics included trypanosome infection and its role in the...
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