Article
COVID-19 Serum Drives Spike-Mediated SARS-CoV-2 Variation.
Viruses - 11 May 2024
Yu Yuanling, Zhang Mengyi, Huang Lan, Chen Yanhong, Wu Xi, Li Tao, Li Yanbo, Wang Youchun, Huang Weijin
Abstract excerpt
Neutralizing antibodies targeting the spike (S) protein of SARS-CoV-2, elicited either by natural infection or vaccination, are crucial for protection against the virus. Nonetheless, the emergence of viral escape mutants presents ongoing challenges by contributing to breakthrough infections. To define the evolution trajectory of SARS-CoV-2 within the immune population, we co-incubated replication-competent...
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