Article
Forecasting early onset diminished ovarian reserve for young reproductive age women.
Journal of assisted reproduction and genetics - 1 Jul 2021
McCallie Blair R, Haywood Mary, Denomme Michelle M, Makloski Rachel, Parks Jason C, Griffin Darren K, Schoolcraft William B, Katz-Jaffe Mandy G
Abstract excerpt
PURPOSE: To investigate the biological networks associated with DOR in young women and the subsequent molecular impact on preimplantation embryos. METHODS: Whole peripheral blood was collected from patients: young women presenting with diminished ovarian reserve (DOR) and age-matched young women with normal ovarian reserve. Maternal exome sequencing was performed on the NovaSEQ 6000 and sequencing validation was...
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