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Association between ovarian reserve and spontaneous miscarriage and their shared genetic architecture

31 Aug 2023

Abstract excerpt

STUDY QUESTION: Can potential mechanisms involved in the likely concurrence of diminished ovarian reserve (DOR) and miscarriage be identified using genetic data? SUMMARY ANSWER: Concurrence between ovarian reserve and spontaneous miscarriage was observed, and may be attributed to shared genetic risk loci enriched in antigen processing and presentation and autoimmune disease pathways. WHAT IS KNOWN ALREADY:...

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Share to Ovarian function and disorders
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37713654
DOI: 10.1093/humrep/dead180

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