Article
FMR1-dependent variability of ovarian aging patterns is already apparent in young oocyte donors.
Reproductive biology and endocrinology : RB&E - 16 Aug 2013
Gleicher Norbert, Kim Ann, Barad David H, Shohat-Tal Aya, Lazzaroni Emanuela, Michaeli Tamar, Lee Ho-Joon, Kushnir Vitaly A, Weghofer Andrea
Abstract excerpt
BACKGROUND: Hypothesizing that redundant functional ovarian reserve (FOR) at young ages may clinically obfuscate prematurely diminished FOR (PDFOR), we investigated in young oocyte donors genotypes and sub-genotypes of the FMR1 gene, in prior studies associated with specific ovarian aging patterns, and determined whether they already at such young age were associated with variations in ovarian reserve (OR). We...
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