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Article

Compromised global embryonic transcriptome associated with advanced maternal age

25 Apr 2019

Abstract excerpt

PURPOSE: To investigate the global transcriptome and associated embryonic molecular networks impacted with advanced maternal age (AMA). METHODS: Blastocysts derived from donor oocyte IVF cycles with no male factor infertility (< 30 years of age) and AMA blastocysts (≥ 42 years) with no other significant female factor infertility or male factor infertility were collected with informed patient consent. RNA...

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PMID: 31025158
DOI: 10.1007/s10815-019-01438-5

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