Article

Identification and Characterization of Atm Founder Germline Mutation in Brca-negative Breast Cancer Patients of Arab Ethnicity

2023-07-31

Abstract excerpt

<h4>Background: </h4> Breast Cancer (BC) is the most prevalent malignancy among women worldwide with germline pathogenic variants/likely pathogenic variants (PVs/LPVs) in BRCA1/2 accounting for a large portion of hereditary cases. Recently, heterozygous PVs/LPVs in the ATM serine/threonine kinase or Ataxia-telangiectasia mutated gene ( ATM ) has been identified as a moderate susceptibility factor for BC in diverse...

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Literature Corpus work: 59b3af97-858b-5e0f-b512-9954db806ab3
DOI: 10.21203/rs.3.rs-3202722/v1

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