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Article

The association of three DNA repair genes polymorphisms on the frequency of chromosomal alterations detected by fluorescence in situ hybridization.

International archives of occupational and environmental health - 1 Oct 2021

Santiago Fábio, Silvestre Rafaele Tavares, Otero Ubirani Barros, Tabalipa Marianne Medeiros, de Moura Ribeiro-Carvalho Marilza, Scherrer Luciano Rios, Al-Rikabi Ahmed, Liehr Thomas, Alves Gilda, Ornellas Maria Helena

Abstract excerpt

PURPOSE: Gas station workers (GSWs) are exposed to carcinogenic agents. The aim was to study the association of high somatic chromosome alterations (CAs) rates in the blood of GSWs and the polymorphisms of three genes playing a role in DNA double-strand break repair. METHODS: This is a cross-sectional study with 114 GSWs and 115 age-matched controls. Cytogenetic analyses, blood exams, medical interviews and...

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Identifiers

PMID: 33778923
DOI: 10.1007/s00420-021-01652-8
PMCID: PMC8384795

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