Article
Polymorphisms in DNA repair genes: link with biomarkers of the CBMN cytome assay in hospital workers chronically exposed to low doses of ionising radiation.
Arhiv za higijenu rada i toksikologiju - 1 Jun 2015
Milić Mirta, Rozgaj Ružica, Kašuba Vilena, Jazbec Ana-Marija, Starčević Boris, Lyzbicki Barnaba, Ravegnini Gloria, Zenesini Corrado, Musti Muriel, Hrelia Patrizia, Angelini Sabrina
Abstract excerpt
Individual sensitivity to ionising radiation (IR) is the result of interaction between exposure, DNA damage, and its repair, which is why polymorphisms in DNA repair genes could play an important role. We examined the association between DNA damage, expressed as micronuclei (MNi), nuclear buds (NBs), and nucleoplasmic bridges (NPBs) and single nucleotide polymorphisms in selected DNA repair genes (APE1, hOGG1,...
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