Article
DNA excision repair and double-strand break repair gene polymorphisms and the level of chromosome aberration in children with long-term exposure to radon.
International journal of radiation biology - 1 Aug 2016
Larionov Aleksey V, Sinitsky Maxim Y, Druzhinin Vladimir G, Volobaev Valentin P, Minina Varvara I, Asanov Maxim A, Meyer Alina V, Tolochko Tatiana A, Kalyuzhnaya Ekaterina E
Abstract excerpt
PURPOSE: To study polymorphic variants of repair genes in people affected by long-term exposure to radon. The chromosome aberration frequency in peripheral blood lymphocytes was used as the biological marker of genotoxicity. MATERIALS AND METHODS: Genotyping of 12 single nucleotide polymorphisms in DNA repair genes (APE, XRCC1, OGG1, ADPRT, XpC, XpD, XpG, Lig4 and NBS1) was performed in children with long-term...
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