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Article

EGF Induces Migration Independent of EMT or Invasion in A549 Lung Adenocarcinoma Cells

12 Mar 2021

Abstract excerpt

Tumors and the tumor microenvironment produce multiple growth factors that influence cancer cell behavior via various signal transduction pathways. Growth factors, like transforming growth factor β (TGFβ) and epidermal growth factor (EGF), have been shown to induce proliferation, migration, and invasion in different cell models. Both factors are frequently overexpressed in cancer and will often act in...

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PMID: 33777943
DOI: 10.3389/fcell.2021.634371

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