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Article

Genetic variants in MAPK10 modify renal cell carcinoma susceptibility and clinical outcomes.

Life sciences - 15 Jun 2021

Tsai Yuan-Chin, Huang Chao-Yuan, Hsueh Yu-Mei, Fan Yu-Ching, Fong Yu-Cin, Huang Shu-Pin, Geng Jiun-Hung, Chen Lih-Chyang, Lu Te-Ling, Bao Bo-Ying

Abstract excerpt

AIMS: The mitogen-activated protein kinase (MAPK) cascades integrate various upstream signals to regulate many cellular functions, including proliferation, differentiation, and survival. Dysregulation of these pathways has been implicated in the occurrence and progression of a variety of cancers. MAIN METHODS: This study aimed to assess the association of 192 single nucleotide polymorphisms in 22 MAPK cascade...

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Identifiers

PMID: 33774030
DOI: 10.1016/j.lfs.2021.119396

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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