Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Epigenetic identification of mitogen-activated protein kinase 10 as a functional tumor suppressor and clinical significance for hepatocellular carcinoma

2 Feb 2021

Abstract excerpt

Background Mitogen-activated protein kinase 10 ( Mapk10 ) is a member of the c-jun N-terminal kinases ( jnk ) subgroup in the MAPK superfamily, and was proposed as a tumor suppressor inactivated epigenetically. Its role in hepatocellular carcinoma (HCC) has not yet been illustrated. We aimed to investigate the expression and epigenetic regulation of mapk10 as well as its clinical significance in HCC. Results...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Mechanisms and Therapy
Share to Epigenetics and DNA Methylation
Share to Ferroptosis and cancer prognosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33604188
DOI: 10.7717/peerj.10810

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Epigenetic identification of mitogen-activated protein kinase 10 as a functional tumor suppressor and clinical significance for hepatocellular carcinomaPMID 33604188Read ↗

Genetic variants in MAPK10 modify renal cell carcinoma susceptibility and clinical outcomes.Semantic proximity Read ↗

Transcriptional Expression of Minichromosome Maintenance 10 as an Independent Negative Predictor of Survival in Hepatocellular CarcinomaSemantic proximity Read ↗

The p38 MAPK Components and Modulators as Biomarkers and Molecular Targets in CancerSemantic proximity Read ↗

miRNA-708 functions as a tumour suppressor in hepatocellular carcinoma by targeting SMAD3Semantic proximity Read ↗

Prognostic significance and function of MCM10 in human hepatocellular carcinoma.Semantic proximity Read ↗

Methylation status of c-fms oncogene in HCC and its relationship with clinical pathology.Semantic proximity Read ↗

NAT10 is upregulated in hepatocellular carcinoma and enhances mutant p53 activity.Semantic proximity Read ↗

Functional Roles of JNK and p38 MAPK Signaling in Nasopharyngeal CarcinomaSemantic proximity Read ↗

Activation of mitogen-activated protein kinases/extracellular signal-regulated kinases in human hepatocellular carcinomaSemantic proximity Read ↗

Clinical and biological significance of Cdk10 in hepatocellular carcinomaSemantic proximity Read ↗

Downregulation of THRSP Promotes Hepatocellular Carcinoma Progression by Triggering ZEB1 Transcription in an ERK-dependent MannerSemantic proximity Read ↗

Down-regulated of PCDH10 predicts poor prognosis in hepatocellular carcinoma patientsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.