Article
Genetic variants in RKIP are associated with clear cell renal cell carcinoma risk in a Chinese population.
PloS one - 1 Jan 2014
Cao Qiang, Wang Jian, Zhang Mingcong, Li Pu, Qian Jian, Zhang Shaobo, Zhang Lei, Ju Xiaobing, Wang Meilin, Zhang Zhengdong, Li Jie, Gu Min, Zhang Wei, Qin Chao, Shao Pengfei, Yin Changjun
Abstract excerpt
BACKGROUND: Raf-1 kinase inhibitor protein (RKIP) plays a critical role in tumor development by regulating cell functions such as invasion, apoptosis and differentiation. Down-regulation of RKIP expression has been implicated in the development and progression of renal cell carcinoma (RCC). Herei...
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