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Neutrophils induce paracrine telomere dysfunction and senescence in ROS‐dependent manner

25 Mar 2021

Abstract excerpt

Cellular senescence is characterized by an irreversible cell cycle arrest as well as a pro-inflammatory phenotype, thought to contribute to aging and age-related diseases. Neutrophils have essential roles in inflammatory responses; however, in certain contexts their abundance is associated with a number of age-related diseases, including liver disease. The relationship between neutrophils and cellular senescence...

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Share to Neutrophil, Myeloperoxidase and Oxidative Mechanisms
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PMID: 33764576
DOI: 10.15252/embj.2020106048

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