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Phenotypes and functions of "aged" neutrophils in cardiovascular diseases.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie - 1 Oct 2024

Ling Shuang, Xu Jin-Wen

Abstract excerpt

Neutrophils are important effector cells of innate immunity and undergo several phenotypic changes after release from the bone marrow. Neutrophils with a late life cycle phenotype are often referred to as "aged" neutrophils. These neutrophils undergo functional changes that accompany stimuli of inflammation, tissue senescence and injury, inducing their maturation and senescence in the circulation and locally in...

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PMID: 39216451
DOI: 10.1016/j.biopha.2024.117324

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