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Targeting the Aryl Hydrocarbon Receptor Signaling Pathway in Breast Cancer Development

8 Mar 2021

Abstract excerpt

Activation of the aryl hydrocarbon receptor (AhR) through environmental exposure to known human carcinogens including dioxins can lead to the promotion of breast cancer. While the repressor protein of the AhR (AhRR) blocks the canonical AhR pathway, the function of AhRR in the development of breast cancer is not well-known. In the current study we examined the impact of suppressing AhR activity using its...

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PMID: 33763068
DOI: 10.3389/fimmu.2021.625346

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