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Article

Environmental exposure and the role of AhR in the tumor microenvironment of breast cancer

15 Dec 2022

Abstract excerpt

Activation of the aryl hydrocarbon receptor (AhR) through environmental exposure to chemicals including polycyclic aromatic hydrocarbons (PAHs) and polychlorinated dibenzo-p-dioxins (PCDDs) can lead to severe adverse health effects and increase the risk of breast cancer. This review considers several mechanisms which link the tumor promoting effects of environmental pollutants with the AhR signaling pathway,...

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Identifiers

PMID: 36588678
DOI: 10.3389/fphar.2022.1095289

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