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Morphofunctional analysis of human pancreatic cancer cell lines in 2- and 3-dimensional cultures

24 Mar 2021

Abstract excerpt

Genetic, transcriptional, and morphological differences have been reported in pancreatic ductal adenocarcinoma (PDAC) cases. We recently found that epithelial or mesenchymal features were enhanced in three-dimensional (3D) cultures compared to two-dimensional (2D) cultures. In this study, we examined the differences in the morphological and functional characteristics of eight PDAC cell lines in 2D and 3D...

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PMID: 33762591
DOI: 10.1038/s41598-021-86028-1

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