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Establishment and Characterization of Paired Primary Cultures of Human Pancreatic Cancer Cells and Stellate Cells Derived from the Same Tumor.

Cells - 16 Jan 2020

Amrutkar Manoj, Larsen Emma Kristine, Aasrum Monica, Finstadsveen Anette Vefferstad, Andresen Per Arne, Verbeke Caroline S, Gladhaug Ivar P

Abstract excerpt

Pancreatic ductal adenocarcinoma (PDAC) is characterized by an extremely poor prognosis, and its treatment remains a challenge. As the existing in vitro experimental models offer only a limited resemblance to human PDAC, there is a strong need for additional research tools to better understand PDAC tumor biology, particularly the impact of the tumor stroma. Here, we report for the first time the establishment and...

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Identifiers

PMID: 31963309
DOI: 10.3390/cells9010227
PMCID: PMC7016771

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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