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Article

Genotype-expression interactions for BDNF across human brain regions.

BMC genomics - 23 Mar 2021

Devlin Patrick, Cao Xueyuan, Stanfill Ansley Grimes

Abstract excerpt

BACKGROUND: Genetic variations in brain-derived neurotrophic factor (BDNF) are associated with various psychiatric disorders including depression, obsessive-compulsive disorder, substance use disorders, and schizophrenia; altered gene expression triggered by these genetic variants may serve to create these phenotypes. But genotype-expression interactions for this gene have not been well-studied across brain...

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PMID: 33757426
DOI: 10.1186/s12864-021-07525-1
PMCID: PMC7989003

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