Article
Polymorphisms in the FAM167A-BLK, but not BANK1, are associated with primary Sjögren's syndrome in a Han Chinese population.
Clinical and experimental rheumatology - 1 Jan 2000
Sun Fei, Xu Juanjuan, Wu Ziyan, Li Ping, Chen Hua, Su Jinmei, You Xin, Li Mengtao, Zhao Yan, Tian Xinping, Li Yongzhe, Zhang Fengchun
Abstract excerpt
OBJECTIVES: Primary Sjögren's syndrome (pSS) is an autoimmune disease with a complex genetic background. Single nucleotide polymorphisms (SNPs) in the BANK1 and FAM167A-BLK genes have been associated with multiple autoimmune diseases. In this study, we investigated whether SNPs in the BANK1 (rs4522865, rs17266594, and rs10516487) and in the FAM167A-BLK region (rs2736340, rs13277113) could be associated with pSS...
