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Article

Identification of MFRP and the secreted serine proteases PRSS56 and ADAMTS19 as part of a molecular network involved in ocular growth regulation.

PLoS genetics - 1 Mar 2021

Koli Swanand, Labelle-Dumais Cassandre, Zhao Yin, Paylakhi Seyyedhassan, Nair K Saidas

Abstract excerpt

Precise regulation of ocular size is a critical determinant of normal visual acuity. Although it is generally accepted that ocular growth relies on a cascade of signaling events transmitted from the retina to the sclera, the factors and mechanism(s) involved are poorly understood. Recent studies have highlighted the importance of the retinal secreted serine protease PRSS56 and transmembrane glycoprotein MFRP, a...

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Identifiers

PMID: 33755662
DOI: 10.1371/journal.pgen.1009458
PMCID: PMC8018652

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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