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Article

MFRP in Early Onset Retinal Degeneration: Clinical and Molecular Perspectives.

Advances in experimental medicine and biology - 1 Jan 2025

Woodard DaNae R, Ayyagari Radha

Abstract excerpt

The membrane-frizzled related protein (MFRP) is a retinal pigment epithelium (RPE) and ciliary epithelium-expressed gene of unknown function. Interest in MFRP stems from clinical manifestations that range from acute-angle closure glaucoma to microphthalmia and Retinitis pigmentosa in patients with MFRP mutations. Furthermore, the genetic ablation of Mfrp in mice results in an early-onset retinal disease with...

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Identifiers

PMID: 39930176
DOI: 10.1007/978-3-031-76550-6_13

Genes

MFRP
RPE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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