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Article

Genomic landscape of biliary tract cancer and corresponding targeted treatment strategies

25 Apr 2025

Abstract excerpt

Biliary tract cancers (BTCs) are classified on the basis of their anatomical origin, and the feasibility of surgical resection depends on the tumor location and extent of progression. However, for unresectable BTCs, systemic therapy has been uniformly applied. Gemcitabine and cisplatin (GC) therapy and GC-based therapies were established as the first-line standard BTC treatment. However, no highly effective...

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PMID: 40281353
DOI: 10.1007/s10147-025-02761-x

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