Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Metabolic Regulation of Thymic Epithelial Cell Function.

Frontiers in immunology - 1 Jan 2021

Semwal Manpreet K, Jones Nicholas E, Griffith Ann V

Abstract excerpt

The thymus is the primary site of T lymphocyte development, where mutually inductive signaling between lymphoid progenitors and thymic stromal cells directs the progenitors along a well-characterized program of differentiation. Although thymic stromal cells, including thymic epithelial cells (TECs) are critical for the development of T cell-mediated immunity, many aspects of their basic biology have been...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy
Share to Cellular Microenvironment
Share to Energy Metabolism

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epithelial Cells

Share to Oxidative Stress

Share to Reactive Oxygen Species

Share to Thymus Gland

Share to TOR Serine-Threonine Kinases

Source

Open in PubMed Open full text

Identifiers

PMID: 33746975
DOI: 10.3389/fimmu.2021.636072
PMCID: PMC7968369

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Metabolic Regulation of Thymic Epithelial Cell Function.PMID 33746975Read ↗

Thymic Epithelial CellsSemantic proximity Read ↗

Cellular metabolism regulates the differentiation and function of T-cell subsetsSemantic proximity Read ↗

Metabolic T-cell phenotypes: from bioenergetics to function.Semantic proximity Read ↗

Autophagy in thymic epithelium shapes the T-cell repertoire and is essential for toleranceSemantic proximity Read ↗

Cell metabolism: Functional and phenotypic single cell approaches.Semantic proximity Read ↗

Metabolic pathways in T cell activation and lineage differentiation.Semantic proximity Read ↗

Redox status regulates autophagy in thymic stromal cells and promotes T cell tolerance.Semantic proximity Read ↗

Contributions of alveolar epithelial cell quality control to pulmonary fibrosis.Semantic proximity Read ↗

Deconstructing the Thymic Microenvironment Through Genesis to SenescenceSemantic proximity Read ↗

The Metabolic Basis of ILC PlasticitySemantic proximity Read ↗

Discovery of thyrocyte heterogeneity reveals an essential role of Notch signaling in thyroid function and mammalian homeostasisSemantic proximity Read ↗

Thymic generation and regenerationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.