Article
A Bioinformatic Pipeline to Identify Biomarkers for Metastasis Formation from RNA Sequencing Data.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2021
Dahlmann Mathias, Stein Ulrike S
Abstract excerpt
Deep molecular characterization of tumors is a prerequisite for precision oncology and personalized anticancer treatment. Analyzing the tumor transcriptome by RNA sequencing (RNAseq) allows the quantification of individual isoforms and also the detection of sequence alteration in the expressed genes. This chapter describes an analysis pipeline that focuses both on accurate quantification of transcripts and on the...
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