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Article

A consensus molecular subtypes classification strategy for clinical colorectal cancer tissues

23 May 2024

Abstract excerpt

Consensus Molecular Subtype (CMS) classification of colorectal cancer (CRC) tissues is complicated by RNA degradation upon formalin-fixed paraffin-embedded (FFPE) preservation. Here, we present an FFPE-curated CMS classifier. The CMSFFPE classifier was developed using genes with a high transcript integrity in FFPE-derived RNA. We evaluated the classification accuracy in two FFPE-RNA datasets with matched...

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PMID: 38782602
DOI: 10.26508/lsa.202402730

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