Article
Newly identified single-nucleotide polymorphism associated with the transition from nonalcoholic fatty liver disease to liver fibrosis: results from a nested case-control study in the UK biobank.
Annals of medicine - 1 Dec 2025
Ling Yitong, Yang Yu Xuan, Chen Yan Chun, Wang Jing Hao, Feng Dong Ge, Xiang Shi Jian, Zhang Xiaoyu, Lyu Jun, Li Sha Sha
Abstract excerpt
BACKGROUND: Genetic factors may have a significant influence on the likelihood of liver fibrosis in individuals with nonalcoholic fatty liver disease (NAFLD). The present study was conducted to explore how single-nucleotide polymorphism (SNP) impacts the development of fibrosis in those suffering from NAFLD. MATERIALS AND METHODS: Utilizing the UK Biobank dataset, we conducted a nested case-control analysis among...
Read the complete abstract on PubMedTopics
- Humans
- Non-alcoholic Fatty Liver Disease
- Liver Cirrhosis
- Case-Control Studies
- United Kingdom