Article
PNPLA3 and SAMM50 variants are associated with lean nonalcoholic fatty liver disease in Asian population.
Annals of hepatology - 1 Jan 2025
Lu Chia-Wen, Chou Tzu-Jung, Wu Tsan-Yu, Lee Yi-Hsuan, Yang Hung-Jen, Huang Kuo-Chin
Abstract excerpt
INTRODUCTION AND OBJECTIVES: Lean adults with nonalcoholic fatty liver disease (NAFLD) have a higher risk of metabolic syndrome than lean controls. The study aimed to investigate the clinical and genetic features of lean NAFLD which remain unclear in Asian populations. MATERIALS AND METHODS: This was a genetic cohort study conducted in the HAVO Health Exam Clinic in 2020-2021 in Taiwan. Adults with a body mass...
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