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LncRNA HCG11 inhibits adipocyte differentiation in human adipose-derived mesenchymal stem cells by sponging miR-204-5p to upregulate SIRT1

2020-06-04

Abstract excerpt

<h4>Background: </h4> LncRNAs have been discovered to play a key role in adipogenesis, vital in regulating adipose developmen t. Numerous evidences show that adipogenesis is the leading cause of obesity, while the role of lncRNA HLA complex group 11 ( HCG11 ) in adipocyte differentiation has not been elucidated. <h4>Methods:</h4> hAdMSCs were used to establish a model of cell differentiation in vitro . Expression...

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Literature Corpus work
6521d821-e733-56de-9df5-14f25a234840
DOI
10.21203/rs.3.rs-31289/v1
Open publication

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