Article
Mesenchymal stem cells-derived exosomal miRNA-28-3p promotes apoptosis of pulmonary endothelial cells in pulmonary embolism
2020-06-19
Abstract excerpt
<title>Abstract</title> <p>Background Pulmonary embolism (PE) is a primary clinical manifestation of venous thromboembolism (VTE). It has been demonstrated that pulmonary endothelial cells (PECs) are apoptotic-resistance in PE. In this study, PECs were collected from PE patients and mouse models. Western blot, RT-PCR, flow cytometry, H&E and TUNEL assay, confocal and TEM microscopy, and luciferase reporter assay...
Topics
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- Apelin-related biomedical research
- Blood Coagulation and Thrombosis Mechanisms
- Cancer-related molecular mechanisms research
- Circular RNAs in diseases
- Extracellular vesicles in disease
- Protease and Inhibitor Mechanisms
- Pulmonary Hypertension Research and Treatments
- Venous Thromboembolism Diagnosis and Management
Identifiers and source
- Literature Corpus work
- 8091359e-f274-57c3-85d3-e19bc6ef6e83
- DOI
- 10.21203/rs.3.rs-36047/v1
