Article
Single nucleotide variations in ZBTB46 are associated with post-thrombolytic parenchymal haematoma.
Brain : a journal of neurology - 4 Sept 2021
Carrera Caty, Cárcel-Márquez Jara, Cullell Natalia, Torres-Águila Nuria, Muiño Elena, Castillo José, Sobrino Tomás, Campos Francisco, Rodríguez-Castro Emilio, Llucià-Carol Laia, Millán Mònica, Muñoz-Narbona Lucía, López-Cancio Elena, Bustamante Alejandro, Ribó Marc, Álvarez-Sabín José, Jiménez-Conde Jordi, Roquer Jaume, Giralt-Steinhauer Eva, Soriano-Tárraga Carolina, Mola-Caminal Marina, Vives-Bauza Cristófol, Navarro Rosa Díaz, Tur Silvia, Obach Victor, Arenillas Juan Francisco, Segura Tomás, Serrano-Heras Gemma, Martí-Fàbregas Joan, Delgado-Mederos Raquel, Freijo-Guerrero M Mar, Moniche Francisco, Cabezas Juan Antonio, Castellanos Mar, Gallego-Fabrega Cristina, González-Sanchez Jonathan, Krupinsky Jurek, Strbian Daniel, Tatlisumak Turgut, Thijs Vincent, Lemmens Robin, Slowik Agnieszka, Pera Johanna, Kittner Steven, Cole John, Heitsch Laura, Ibañez Laura, Cruchaga Carlos, Lee Jin-Moo, Montaner Joan, Fernández-Cadenas Israel
Abstract excerpt
Haemorrhagic transformation is a complication of recombinant tissue-plasminogen activator treatment. The most severe form, parenchymal haematoma, can result in neurological deterioration, disability, and death. Our objective was to identify single nucleotide variations associated with a risk of parenchymal haematoma following thrombolytic therapy in patients with acute ischaemic stroke. A fixed-effect genome-wide...
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