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Article

Blood gene expression studies in migraine: Potential and caveats.

Cephalalgia : an international journal of headache - 1 Jun 2016

Gerring Zachary, Rodriguez-Acevedo Astrid J, Powell Joseph E, Griffiths Lyn R, Montgomery Grant W, Nyholt Dale R

Abstract excerpt

BACKGROUND: Global gene expression analysis may be used to obtain insights into the functional processes underlying migraine. However, there is a shortage of high-quality post-mortem brain tissue samples for genetic analysis. One approach is to use a more accessible tissue as a surrogate, such as peripheral blood. PURPOSE: Discuss the benefits and caveats of blood genomic profiling in migraine and its potential...

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PMID: 26862113
DOI: 10.1177/0333102416628463

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