Article
Variation in coagulation and fibrinolysis genes evaluated for their contribution to cerebrovascular complications in adults with bacterial meningitis in the Netherlands.
The Journal of infection - 1 Jul 2018
Kloek A T, Khan H N, Valls Seron M, Jongejan A, Zwinderman A H, Baas F, van der Ende A, van de Beek D, Ferwerda B, Brouwer M C
Abstract excerpt
OBJECTIVE: To study whether genetic variation in coagulation and fibrinolysis genes contributes to cerebrovascular complications in bacterial meningitis. METHODS: We performed a nationwide prospective genetic association study in adult community-acquired bacterial meningitis patients. The exons and flanking regions of 16 candidate genes involved in coagulation and fibrinolysis pathways were sequenced. We analyzed...
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