Article
The association between family history and genomic burden with schizophrenia mortality: a Swedish population-based register and genetic sample study.
Translational psychiatry - 15 Mar 2021
Kowalec Kaarina, Lu Yi, Song Jie, Dalman Christina, Hultman Christina M, Larsson Henrik, Lichtenstein Paul, Sullivan Patrick F
Abstract excerpt
Individuals with schizophrenia (SCZ) have a 2-3-fold higher risk of mortality than the general population. Heritability of mortality in psychiatric disorders has been proposed; however, few have investigated SCZ family history and genetic variation, with all-cause and specific causes of death. We aimed to identify correlates of SCZ mortality using genetic epidemiological and genetic modelling in two samples: a...
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