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Article

Association between the promoter haplotype of RTN4 gene and schizophrenia in a Korean population.

Psychiatry research - 1 May 2021

Park Hae Jeong, Kang Won Sub, Kim Jong Woo

Abstract excerpt

Previous studies have suggested the involvement of Nogo-A/RTN4 in the pathogenesis of schizophrenia. We investigated an association between the promoter haplotypes of RTN4 comprised of rs1348528-rs1822618-rs2241958 and schizophrenia. A significant association between the rare TGA haplotype and schizophrenia was shown (p < 0.0001). Additionally, the promoter activity was profoundly decreased by the TGA haplotype....

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Share to Genetic Predisposition to Disease
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Identifiers

PMID: 33721786
DOI: 10.1016/j.psychres.2021.113841

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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