Article
No association between the genetic polymorphisms in the RTN4R gene and schizophrenia in the Chinese population.
Journal of neural transmission (Vienna, Austria : 1996) - 1 Feb 2007
Meng J, Shi Y, Zhao X, Guo S, Wang H, Zheng Y, Tang R, Feng G, Gu N, Liu H, Zhu S, He L
Abstract excerpt
The RTN4R gene is located in the 22q11 region and it encodes a subunit of the receptor complex (RTN4R-p75NTR) which results in neuronal growth inhibitory signals in response to Nogo-66, MAG or OMG signaling. Previous studies have suggested that RTN4R might act as a potential candidate for schizophrenia susceptibility loci. We genotyped four SNPs within the gene and conducted a case-control study and TDT analysis,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
