Article
Endometrial Adenocarcinomas With No Specific Molecular Profile: Morphologic Features and Molecular Alterations of "Copy-number Low" Tumors.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists - 1 Nov 2021
Meljen Vivienne T, Mittenzwei Rhonda, Wong Janice, Puechl Allison, Whitaker Regina, Broadwater Gloria, Hall Allison H, Bean Sarah M, Bentley Rex C, Elvin Julia A, Berchuck Andrew, Previs Rebecca A, Strickland Kyle C
Abstract excerpt
The study evaluated morphologic patterns, mutational profiles, and β-catenin immunohistochemistry (IHC) in copy-number low (CNL) endometrial adenocarcinomas (EAs). CNL EAs (n=19) with next-generation or whole genome sequencing results and available tissue for IHC were identified from our institutional database. Clinical data and histologic slides were reviewed. IHC for β-catenin was performed and correlated with...
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