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Aurora Kinase B Expression, Its Regulation and Therapeutic Targeting in Human Retinoblastoma

11 Mar 2021

Abstract excerpt

Purpose: Aurora kinase B (AURKB) plays a pivotal role in the regulation of mitosis and is gaining prominence as a therapeutic target in cancers; however, the role of AURKB in retinoblastoma (RB) has not been studied. The purpose of this study was to determine if AURKB plays a role in RB, how its expression is regulated, and whether it could be specifically targeted. Methods: The protein expression of AURKB was...

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PMID: 33704359
DOI: 10.1167/iovs.62.3.16

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