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Article

Association of the STAT4, CDKN1A, and IRF5 variants with risk of lupus nephritis and renal biopsy classification in patients in Vietnam.

Molecular genetics & genomic medicine - 1 Apr 2021

Nghiem Trung Dung, Do Gia Tuyen, Luong Long Hoang, Nguyen Quy Linh, Dang Ha Viet, Viet Anh Nguyen, Nguyen Thuy Thu, Tran Van Khanh, Ta Thanh Van, Tran Thinh Huy

Abstract excerpt

BACKGROUND: Lupus nephritis is a common complication of systemic lupus erythematosus (SLE, OMIM #15200) in the Asian population and a main contributor to mortality and morbidity. In this study, we evaluate the variants on three genes STAT4, CDKN1A, and IRF5 and their association with lupus nephritis. METHOD: One hundred fifty-two SLE patients with confirmed lupus nephritis (through biopsy) and 76 healthy controls...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 33687153
DOI: 10.1002/mgg3.1648
PMCID: PMC8123735

Genes

STAT4
CDKN1A

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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